News / ‘Be more vigilant’ message to forwarders on potentially dangerous shipments

first_img© Hupeng | Dreamstime.com By Alexander Whiteman 24/09/2018 Forwarders need to improve levels of due diligence to avert the risks to cargo security, with e-commerce lowering the industry’s barrier to entry.Senior loss prevention executive at TT Club Mike Yarwood told The Loadstar the wider industry needed to play its role in facilitating this.“It’s about empowering all the forwarders to ask the relevant questions with the necessary knowledge for the shipment in hand,” he said.“Once the due diligence is done, it’s then about turning to the goods in transit and making sure they are transported under the right conditions and that these are maintained.”center_img Mr Yarwood said forwarders needed to ask, on every shipment, what is being shipped, where it is being shipped to and who their customers are.However, he believed the rise of e-commerce had made the job harder, by lowering the bars to entry and leaving many forwarders unaware that they may be shipping dangerous goods.“As an example, not everyone realises that airbag components are classed as dangerous goods – the mechanism that releases them is classed as an explosive,” he said.“This is not to say all forwarders have little knowledge of the markets, but it is important that they know what their responsibilities are.”To address this, Mr Yarwood called on regulators, industry bodies and governments to put greater emphasis on improving the visibility of the CTU Code.Adopted in 2014, CTU is the industry’s first code of practice for cargo security and, while regarded as non-mandatory in international law, Mr Yarwood implored more forwarders to follow it.“It not only tells forwarders and shippers who must be doing what, but it also lays out the guidelines on culpability when accidents do occur,” he said.“These responsibilities are set out and works on a case-by-case basis with judgements made on individual merits.“It’s about empowerment and knowledge, and this is where the CTU Code excels and this is why all forwarders should make themselves familiar with it,” he said.last_img read more

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How to rule a gene galaxy: A lesson from developing neurons

first_img“Coherent regulation of multiple genes can pose substantial logistical problems, akin running a successful business employing thousands of people or controlling the vast Galactic Empire from the Star Wars movies” remarks Dr. Eugene Makeyev, a senior author of the study from the MRC CDN. “Our work suggests that fine-tuning messenger stability is an important mechanism orchestrating gene expression changes during normal brain development”.Defective regulation of messenger stability, cellular localization and translation into corresponding protein products often leads to serious medical conditions including neurodegenerative diseases and cancer. A subset of the TTP/miR-9 target genes have been previously linked to these disorders and it will be important to determine whether deregulation of TTP or/and miR-9 plays a causative role in such pathological contexts.Moreover, by uncovering a hitherto unknown mechanism mediating neuronal differentiation, the study by Makeyev and co-authors should facilitate development of novel cell replacement therapies for neurological and neurodegenerative diseases. “Natural renewal of neurons in the adult brain is notoriously inefficient and it likely becomes virtually non-existent as we grow older. With a continued increase in the average life expectancy neuron replacement might become a common medical procedure at some point in the future. Luke Skywalker and his aging father would certainly relate to this idea”. LinkedIn Email Share The human organism contains hundreds of distinct cell types that often differ from their neighbours in shape and function. To acquire and maintain its characteristic features, each cell type must express a unique subset of genes. Neurons, the functional units of our brain, develop through differentiation of neuronal precursors, a process that depends on coordinated activation of hundreds and possibly thousands of neuron-specific genes.A new study published in Nature Communications by researchers from the MRC Centre for Developmental Neurobiology (MRC CDN) at IoPPN, carried out in collaboration with the Tian lab at the Rutgers New Jersey Medical School (USA), unravels how this synchrony is achieved at the molecular level. The researchers found that many RNA messengers encoding neuronal proteins contain specialized sequences that can promote their destabilization in the presence of an RNA-binding protein called tristetraprolin, or TTP.This protein is expressed at relatively high levels in proliferating precursors and non-neuronal cells but down-regulated in developing neurons by a brain-enriched regulatory RNA called miR-9. The TTP/miR-9 pair functions as a switch limiting unscheduled accumulation of neuronal messengers in non-neuronal cells and ensuring coordinated accumulation of these molecules in neurons.center_img Share on Facebook Pinterest Share on Twitterlast_img read more

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Just the tonic

first_imgTo access this article REGISTER NOWWould you like print copies, app and digital replica access too? SUBSCRIBE for as little as £5 per week. Would you like to read more?Register for free to finish this article.Sign up now for the following benefits:Four FREE articles of your choice per monthBreaking news, comment and analysis from industry experts as it happensChoose from our portfolio of email newsletterslast_img

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Badminton world No. 1 Kento Momota slightly injured in crash in Malaysia; driver dies

first_imgKUALA LUMPUR – A van carrying Japan’s Kento Momota, the world No. 1 men’s badminton player, crashed into a truck early Monday morning, killing the driver, while Momota and three other passengers escaped with only slight injuries.The accident came just hours after Momota won the Malaysia Masters. Japanese coach Yu Hirayama, trainer Akifumi Morimoto and William Thomas of England were also on board, according to a statement from the Fire and Rescue Services Department. KEYWORDS Kento Momota poses with his medal after winning the Malaysia Masters on Sunday in Kuala Lumpur. | AP IN FIVE EASY PIECES WITH TAKE 5 badminton, Kento Momota, Malaysia Masters center_img RELATED PHOTOS According to a statement from the Serdang district police, Momota suffered a broken nose as well as injuries to his lips and face.The accident happened on a major highway before dawn as the group headed for Kuala Lumpur International Airport in a van, official news agency Bernama reported.“The victim’s body and all the injured were sent to” a hospital in the administrative capital Putrajaya, Norazam Khamis, a senior official from the Depart of Fire and Rescue Services, was cited as saying.Hours before the crash, Momota had easily defeated Denmark’s Viktor Axelsen 24-22, 21-11 in a boost for his preparations for the Tokyo Olympics.The 25-year-old enjoyed a stellar 2019 season, winning a record 11 titles, including the World Championships, Asia Championships and All England Open.“It’s truly tragic, especially involving a badminton icon like Momota,” Malaysian sports minister Syed Saddiq told reporters, after visiting the injured in a hospital south of the capital.But he added that those hurt were “recovering well, (and) all four are also in stable condition”.The others hurt suffered facial, leg, hand and head injuries, according to the police. GET THE BEST OF THE JAPAN TIMESlast_img read more

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Warriors march towards the post-season

first_imgRound 17 of Big V basketball was an important one for the Pakenham Warriors as they picked some crucial wins….[To read the rest of this story Subscribe or Login to the Gazette Access Pass] Thanks for reading the Pakenham Berwick Gazette. Subscribe or Login to read the rest of this content with the Gazette Digital Access Pass subscription. By Hayley Wildes last_img

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Kinders first choice

first_imgBy KATELYN PINAL CARDINA’S new kindergarten enrolment system has been judged a success with a majority of families receiving offers…[To read the rest of this story Subscribe or Login to the Gazette Access Pass] Thanks for reading the Pakenham Berwick Gazette. Subscribe or Login to read the rest of this content with the Gazette Digital Access Pass subscription.last_img

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